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KMID : 0370220210650040321
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Yakhak Hoeji
2021 Volume.65 No. 4 p.321 ~ p.330
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Establishment of a Functional Reporting Model According to the Content of Active Ingredients in Functional Foods
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Kim Suk-Won
Kim Sun-Jo
Anh Nguyen Hoang
Jung Cheol-Woon
Kwon Sung-Won
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Abstract
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As the market of the functional foods is expanding to general foods, more efficient and accessible methods arerequired to provide quantitative and scientific evidences. In this study, we conceptualized and established a functionalreporting model with logistic regression using the clinical data retrieved from the published literature. The model wasvalidated with two active ingredients, vitamin E and lycopene. A search through PubMed using “tocopherol” or“tocotrienol” or “Vitamin E” as the keywords resulted in 45 data points corresponding to 35 studies in which the antiinflammatoryefficacy of vitamin E was evaluated. The other search through PubMed using “lycopene” as a keywordresulted in 39 data points corresponding to 29 studies in which the antioxidant efficacy of lycopene was evaluated. Weused C-reactive protein (CRP) or high sensitivity C-reactive protein (hs-CRP) as the inflammatory markers, and DNAdamage, lipid, and protein oxidation for the measurement of antioxidant efficacy. According to our model, daily intake ofat least 584.05 mg of vitamin E and 17.85 mg of lycopene is recommended to induce the functional effects. In conclusion,we anticipate that this approach to the functional report modeling would greatly expand the market of functional foods,especially for the native crops.
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KEYWORD
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Logistic regression, Vitamin E, Lycopene, Functional food
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